P. A. Janmey investigated how networks of cytoskeletal proteins bear mechanical loads. A 1991 study compared purified actin, tubulin and vimentin assemblies under deformation. The networks differed in stiffness and resistance to disruption, with vimentin networks especially able to withstand large deformations.[ref]
Viscoelastic properties of vimentin compared with other filamentous biopolymer networks by P. A. Janmey and others. Abstract and pp. 155–160: parallel viscoelastic measurements
The comparison separated the mechanical properties of a filament network from the complexity of an intact cell. A material's response to a small deformation does not completely predict whether it survives a large one. This connects cytoskeleton composition to the distinct questions of stiffness, viscoelasticity and mechanical resilience.
Portrait of P. A. Janmey
. Identified University of Pennsylvania physiology portrait; institutional profile describes cytoskeletal rheology research. Source. Articles by others on the same topic
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