Write , , and . In bits the mutual information is
Terms with zero joint probability contribute zero. On its positive support apply with :
Equality requires equality in every logarithmic inequality and no product mass outside the joint support, hence everywhere. Conversely that factorization makes every term zero. Thus mutual information is nonnegative and vanishes exactly for independence. For countable alphabets the same conclusion follows from the relative-entropy inequality, allowing the value .

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