For the Poisson regression, the log-likelihood is
Since , the score function and its derivative are
Consequently a finite maximum-likelihood estimator satisfies
These nonlinear equations are normally solved by iteratively reweighted least squares. If has full column rank, the Hessian is negative definite and any finite solution is the unique maximizer. Full rank does not by itself rule out a boundary solution at infinite coefficients for every conceivable data set. The Poisson generalized linear model has dispersion one, so there is no separate scale parameter in this likelihood.

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