Let and take an observable with no explicit time dependence. In the Schrödinger picture, and . In the Heisenberg picture, and . For the interaction picture choose a time-independent splitting , put , and define
Then and . Unitarity gives the identical expectation in all three descriptions:
Different choices of the split interpolate between pictures; makes the state constant, while gives the Schrödinger description.
Differentiate to obtain the Heisenberg equation of motion
For an explicitly time-dependent observable there is additionally . Thus is constant. In a normalized energy eigenstate, , so the expectation of its Heisenberg derivative vanishes whenever the products are defined.
For the harmonic oscillator, the canonical commutator gives
The last identity follows from the operator product rule without commuting and . Although is not itself self-adjoint, the same calculation can be applied to the self-adjoint dilation observable and gives the same derivative.
Stationarity of the three expectations gives and . Substitution into yields the quantum virial theorem
The vanishing means make the variances equal to the second moments, so
This satisfies the position-momentum Heisenberg uncertainty relation, with equality only for the ground state.

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