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Joined 2026-09-21 Message
Incoming links: Radiobiology
John Francis Fowler Created 2026-10-24 Updated 2026-11-05
A physicist who applied radiobiology to the comparison of radiation therapy schedules. His work on the linear-quadratic radiobiology model explains why equal total absorbed doses can produce different biological effects when delivered in different-sized fractions. The model separates contributions linear and quadratic in the dose per fraction, while a comparison of schedules must also consider tissue recovery and proliferation over time. This work helped turn a statement of delivered energy into a model of biological response.[ref]
The linear-quadratic formula and progress in fractionated radiotherapy by John Francis Fowler. Introduction: radiobiological basis of fractionation, dose per fraction and delayed proliferation