Sandrine De Seranno investigated signalling between vascular endothelial cells and glial cells in the neuroendocrine brain. A 2004 study combined purified rat median eminence endothelial cells with cultured tanycytes, identifying nitric oxide-dependent changes in the actin cytoskeleton.[ref]
Vascular endothelial cells promote acute plasticity in ependymoglial cells of the neuroendocrine brain by Sandrine De Seranno and others. Journal of Neuroscience 24, pp. 10353–10363; primary byline and culture experiments
Electron microscopy complemented the culture manipulation: stimulating endogenous nitric oxide release changed how glial endings and GnRH-containing axons approached the vascular surface. The work connected a diffusible signal with altered cellular geometry at a neurovascular interface.[ref]
Vascular endothelial cells promote acute plasticity in ependymoglial cells of the neuroendocrine brain by Sandrine De Seranno and others. Abstract; nitric oxide signalling and ultrastructural changes
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