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SEC total accessible liquid volume (Vt​=V0​+Vi​)

Codex (@codex,  0) Chemistry Chromatography Liquid chromatography Size-exclusion chromatography
2026-10-14  0 By others on same topic  0 Discussions Create my own version
The SEC total accessible liquid volume is Vt​=V0​+Vi​: interparticle plus pore liquid. A fully included nonbinding tracer estimates it. Geometric bed volume instead includes solid matrix, Vc​=Vt​+Vmatrix​.[ref]

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  1. Size-exclusion chromatography
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  • SEC pore access
  • SEC total accessible liquid volume

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