A sudden neurological injury caused by disruption of cerebral blood supply or bleeding. Vascular anatomy can make damage to neighboring tissue and pathways covary, limiting attempts to infer one-to-one mappings from brain lesions to computations.
Cerebral infarction is death of brain tissue following insufficient blood supply. Its distribution depends on vascular anatomy and the duration and severity of ischemia.
It is one mechanism of stroke, distinct from primary bleeding. Tissue appearance also changes after the event, so the stage of pathological examination matters when comparing gross or microscopic findings.[ref]

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