A translocon is membrane machinery through which a polypeptide chain crosses or enters a membrane. In endoplasmic reticulum protein targeting, the Sec61 complex supplies the central channel.[ref]
Membrane Protein Insertion at the Endoplasmic Reticulum by Sichen Shao and Ramanujan S. Hegde. Shao and Hegde, 2011; “The Sec61 Translocon”, Figure 4
The Sec61 complex supports passage across the endoplasmic reticulum membrane and lateral entry of membrane-spanning segments into its lipid bilayer.[ref]
Membrane Protein Insertion at the Endoplasmic Reticulum by Sichen Shao and Ramanujan S. Hegde. Shao and Hegde, 2011; “The Sec61 Translocon”, Figure 4
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