Primary article by Judah Folkman, New England Journal of Medicine 285, 1182–1186, November 18, 1971; DOI 10.1056/NEJM197111182852108. Publisher preview identifies the author and Department of Surgery, Children’s Hospital Medical Center and Harvard Medical School. The article frames tumor cells and capillary endothelial cells as interacting populations and proposes therapeutic implications of angiogenesis dependence.

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