A unique molecular identifier is a short sequence tag attached so that observations derived from the same original molecule can be grouped. It helps distinguish amplification duplicates from independently captured templates. If two originals receive the same tag, a collision can merge them; sequence errors can instead split one tag into several apparent groups. The tag space, assignment method and error correction therefore limit molecule-count accuracy. [ref]
Counting absolute numbers of molecules using unique molecular identifiers by Teemu Kivioja and others. Kivioja and others, 2012, molecular tagging and counting principle
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