Section 2 defines entrywise objective, max-entry constraint, symmetric selection and column linear programs. Positive definiteness is a theorem under assumptions, not a program constraint.
Tony Cai 2026-11-05
Tony Cai develops methods and theory for high-dimensional statistics, statistical decision theory and statistical machine learning. His research includes functional data analysis and applications to genomics.[ref]
With Weidong Liu and Xi Luo, he introduced CLIME, estimating a sparse precision matrix through linear programming. Their results bound estimation error under sparsity and tail assumptions. The method makes a useful distinction between an optimization constraint and a theorem: positive definiteness of the final estimate is established under conditions, rather than imposed as a constraint in the columnwise programs.[ref]
Figure 1.
Tony Cai
. Portrait identified on the linked official researcher profile; photographer and licence are not asserted. Source.
Weidong Liu 2026-11-05
Weidong Liu works on high-dimensional statistics. Shanghai Jiao Tong University's institutional profile identifies this researcher and his focus on high-dimensional statistical inference.[ref]
His CLIME paper with Tony Cai and Xi Luo estimates a sparse precision matrix even when direct inversion of the sample covariance matrix is unsuitable. It controls while minimizing an entrywise absolute-value objective, then uses a symmetrization rule. Statistical accuracy requires assumptions on sparsity and the distribution's tails.[ref]
Xi Luo 2026-11-05
Xi Luo develops biostatistics and machine learning methods for biomedical data. His institutional profile identifies applications in neuroscience, genomics and disease research.[ref]
With Tony Cai and Weidong Liu, he developed CLIME for sparse precision matrix estimation. The method constrains the error of an approximate inverse of the sample covariance matrix and minimizes an entrywise absolute-value objective. Its computation separates into columnwise linear programs.[ref]