Ciro Santilli @cirosantilli 35

A function $\mathbb{R}\to \mathbb{R}$ defined by the second of the Josephson equations plus initial conditions.

It represents an internal state of the junction.

This is just the most charming of the Four Great Classic Novels.

The definitive television series adaptation is obviously Journey to the West. It just manages to capture all the charms of Sun Wukong and Zhu Bajie.

A theorem that is not very important on its own, often an intermediate step to proving something that the author feels deserves the name "theorem".

Allows you to connect two adjacent pins of a pin header. Sometimes used as a hardware configuration interface!

Ciro Santilli was contributing to this, when CommonMark left private mode and killed it, thus wasting many hours of Ciro's time.

See also: Ciro Santilli's minor projects.

Creator of Primer

youtube.fandom.com/wiki/Primer gives real identity:Feels exactly the background you'd expect: disilusioned by the educational system, and working to make education better! Great guy! Reminds Ciro Santilli of himself a bit.

Face reveal at: www.youtube.com/watch?v=QC91Bf8hQVo

www.biorxiv.org/content/10.1101/2022.09.19.508583v1.fullIt is also interesting to see how they are interested in co-culture with HeLa cells, presumably to enable infectious bacterial disease studies.

At biology.indiana.edu/news-events/news/2023/lennon-minimal-cells.html (2023) they let it re-evove to it it would regain some fitness, and it did.

Mentinoned at en.wikipedia.org/wiki/Jim_Baggott quoting popsciencebooks.blogspot.com/2012/09/jim-baggott-four-way-interview.html

Ciro Santilli and Jim would get along mighty well: there is value in tutorials written by beginners.

Two equations derived from first principles by Brian Josephson that characterize the device, somewhat like an I-V curve:where:

Note how these equations are not a typical I-V curve, as they are not an instantaneous dependency between voltage and current: the history of the voltage matters! Or in other words, the system has an internal state, represented by the Josephson phase at a given point in time.

To understand them better, it is important to look at some important cases separately:

The fact that they kept the standard open source makes them huge heroes, see also: closed standard.

Shame that many (most?) of their proposals just die out.

E.g. in humans the adenine nucleotide translocator is present in chromosome 4, not in mtDNA.

These have almost certainly been transferred to nuclear DNA in the course of evolution.

This isn't completely surprising, since when mitochondria die, their DNA is kind of left in the cell, so it is not hard to imagine how genes end up getting uptaken by the nucleus. This is suggested at Power, Sex, Suicide by Nick Lane (2006) page 196.

A limiting factor appears to be that you can't just past those genes in the nucleus, further mutations are necessary for mitochondrial protein import to work, apparenty some kind of tagging with extra amino acids.

However, you likely don't want to remove all genes from the mitochondria because mitochondria have DNA because they need to be controlled individually.