Myoglobin structure resolution (1958) by Ciro Santilli 35 Updated 2025-01-10 +Created 1970-01-01
Published at: a Three-Dimensional Model of the Myoglobin Molecule Obtained by X-Ray Analysis (1958). The work was done at the Cavendish Laboratory.
Key mitochondrial proteins aren't necessarily in mtDNA by Ciro Santilli 35 Updated 2025-01-10 +Created 1970-01-01
These have almost certainly been transferred to nuclear DNA in the course of evolution.
This isn't completely surprising, since when mitochondria die, their DNA is kind of left in the cell, so it is not hard to imagine how genes end up getting uptaken by the nucleus. This is suggested at Power, Sex, Suicide by Nick Lane (2006) page 196.
A limiting factor appears to be that you can't just past those genes in the nucleus, further mutations are necessary for mitochondrial protein import to work, apparenty some kind of tagging with extra amino acids.
However, you likely don't want to remove all genes from the mitochondria because mitochondria have DNA because they need to be controlled individually.
Microbit simulator using some Microsoft framework.
TODO the Python code from there does not seem to run on the microbit via
uflash
, because it is not MicroPython.support.microbit.org/support/solutions/articles/19000111744-makecode-python-and-micropython explains.
forum.makecode.com/t/help-understanding-local-build-options/6130 asks how to compile locally and suggests it is possible. Seems to require Yotta, so presumably compiles?
Presumably this is because Microsoft ported their MakeCode thing to the MicroBit, and the Micro Bit foundation accepted them.
E.g. there toggling a LED:but the code that works locally is a completely differently named API Microsoft going all in on adopt extend extinguish from an early age!
led.toggle(0, 0)
set_pixel
:microbit.display.set_pixel(0, 0, )
CC BY-NC-SA unfortunately.
Upload is actually optional, and it appears that teachers do retain their copyright: ocw.mit.edu/ans7870/global/MIT_OpenCourseWare_FAQs.pdf Hmmm, so how have they convinced so many teachers to do it?
Plutonium-based.
Its plutonium was produced at Hanford site.
Respect. Big respect. Those people are hardcore from scratch hackers, and their wiki is amazing: wiki.archlinux.org/
It's just that Buildroot is more hardcore ;-)
But can you build the ISO full from source: Linux distribution buildable from source
Documents the Linux kernel. Somewhat of a competitor to Linux Kernel Module Cheat, but more wordy and less automated.
The opposite of spacelike-separated events.
Experiments: speed of light experiments.
Classification of k-transitive groups by Ciro Santilli 35 Updated 2025-01-10 +Created 1970-01-01
TODO this would give a better motivation for the Mathieu group
async
is all present in JavaScript for two reasons:- you make network requests all the time
- JavaScript is single threaded, so if you are waiting for a network request, the UI freezes, see remarks on the deprecation of synchronous HTTP request at: developer.mozilla.org/en-US/docs/Web/API/XMLHttpRequest/Synchronous_and_Asynchronous_Requests
However, it is also Hell: how to convert
async
to sync in JavaScript. Loop-mediated isothermal amplification by Ciro Santilli 35 Updated 2025-01-10 +Created 1970-01-01
Like PCR, but does not require thermal cycling. Thus the "isothermal" in the name: iso means same, so "same temperature".
Not needing the thermo cycling means that the equipment needed is much smaller and cheaper it seems.
This is perhaps the most popular version of Great doubt in 21st century China
Fuller quote as seen e.g. at: www.hrfjw.com/fjrw/hcrw/ywfs/324750.htmltranslation;
大疑大悟,小疑小悟,不疑不悟
Great doubt, great underestanding. Small doubt, small understanding. No doubt, no understanding.k.sina.cn/article_5668613235_151e02c7300100wutq.html attributes it to modern day Chinese "Master Chongci" (崇慈法师).
Their UI is horrendous as of 2020:
I need this for OurBigBook.com!! webmasters.stackexchange.com/questions/104241/can-google-analytics-track-url-fragment-in-url
They removed referrer path completely in GA4... OMG WTF are they doing!
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