Logic synthesis by Ciro Santilli 37 Updated 2025-07-16
The output of this step is another Verilog file, but one that exclusively uses interlinked cell library components.
Dulong-Petit law by Ciro Santilli 37 Updated 2025-07-16
Observation that all solids appear to have the same constant heat capacity per mole.
It can be seen as the limit case of an Einstein solid at high temperatures. At lower temperatures, the heat capacity depends on temperature.
Social inequality by Ciro Santilli 37 Updated 2025-07-16
Ciro Santilli is extremely passionate about this issue, partly due to Ciro Santilli's self perceived compassionate personality.
Ciro Santilli's main approaches to reduce it:
We have to be careful not to make everyone poorer when trying to reduce inequality.
But as things stand as of 2020, increasing taxes on the very richest, and notably wealth tax, and investing it in free gifted education, seems like a safe bet to achieve any meaningful level of equal opportunity and meritocracy.
Bisulfite sequencing by Ciro Santilli 37 Updated 2025-07-16
The main way to sequence DNA methylation. Converts methylated cytosine to uracil, and then we can sequence those.
Video 1.
Bisulfite Sequencing by Henrik's Lab (2020)
Source. Nothing much new that we don't understand from a single sentence in the animation. But hey, animations!
Why is it there such a clear separation of phases?
Why do people with mild symptoms go on to die? It is a great mystery.
Ciro Santilli's theory is that COVID is extremely effective at avoiding immune response. Then, in people where this is effective, things reach a point where there is so much virus, that the body notices and moves on to take a more drastic approach. This is compatible with the virus killing older people more, as they have weaker immunes systems. This is however incompatible with the fact that people don't seem to be contagious after the viral phase is over...
Rickrolling lyrics were mined several times into the blockchain.
The first currently known instance is as a link right during the prayer wars on block 142573 (2011-08-25) as the miner message:
Militant atheists, bit.ly/naNhG2 -- happy now?"
which redirects to www.youtube.com/watch?v=mGDuExhS6Nw&blockchain
Around block block 246k (e.g. 27b7c526489dac8245747fa1c425a2e3eb07dea57b294eb4ae583fec9b859fcf, 2013-10-17) we note several transactions starting with a XML format <CG SZ="1156"><MG>... the first one being 0b4efe49ea1454020c4d51a163a93f726a20cd75ad50bb9ed0f4623c141a8008 As mentioned not very clearly at www.righto.com/2014/02/ascii-bernanke-wikileaks-photographs.html#ref12 the content of the first <MG><payload></MG> is a Base64 encoded string
Catagory: Poetry
Title: Never Gonna Give You Up
Performer: Rick Astley
Writer: Mike Stock, Matt Aitken, Pete Waterman
Label: RCA Records
followed by lyrics also base64 encoded as part of the XML metadata. Hidden surprises in the Bitcoin blockchain by Ken Shirriff (2014) was not able to identify the exact format either. At twitter.com/EMBII4U/status/1655831533750562816 EMBII mentions that this was part of an upload test.
tx 15b11e8d4e5b9425f024b381ba0cb7a54a35e52389bb4855f505772ce685b39c (2014-06-24): starting from this transaction, the lyrics were inscribed several times via input scripts. Then again:
  • 8bb9db70e24202fdfd0e48b57a11a407e6c8c0e76d879634b801b4345b8810b2
  • b881afa519804a3c93a3c99481517ca8ae070b84c04e8e7a2bfb808e043f9771
  • 70c8405bd0ec10bea49b78a819dfbf46c1082e7e620588f9da65a90b71e52bbd
  • fc4e382793757858bec4b87527caa4bf2e6f71bb2f5a77bb41a45ddb9ed9d409
  • f011e71b711aa54a0c824244fff83fb8b1e1921804624fa0523a6e61612b7f6f
  • a8691cdbca5b82e4e48812e48b7a09e4757801fd3909a09975de957d1bfb52dc
  • d8946aa464be464674bba6d15729d75572ec75dda49fe7ff0ede1a25ca054941
  • d02864cd57c9d041dbd9d6f24327f347b92697a8bc3c86cdf8b738063c6ad002
  • 9b78962d840f1ff681e5042264e4d0359cda98ce49d97569df14ce956622b966
  • 7bdc22fb35f0a8eb6241782a306a8904fb6f793126ff106a04a96f9f223cb8e1
  • e24a4085c54a6362e615f8eab758c12d80e488b73757e6d2b8ab6bfc8be7007e
  • 4257f4980955d8376ee1c6bccb4396da726e4ae13d758e47dc4e0775019723f5
  • a09b49e9374d43386a6a986944e3dcf515c7e1c38324836df5333b8adbe57797
  • 03096688dbb874f7c571691e4241a298284bf4184be339b148f1b48f383a1d7c
  • 62f8b228b6126354736d36d9f3b91882bb81eca7702b74fba6471abc7db96a03 (2015-09-30)
They were mega obnoxious!!! Who does this kind of crap for more than one year!!!
Proof that the probability 1 is conserved by the time evolution:
It can be derived directly from the Schrödinger equation.
Bibliography:
If you live in the relatively food abundant environment of another cell, then you don't have to be able to digest every single food source in existence, of defend against a wide range of predators.
And likely you also want to be as small as possible to evade the host's immune system.
Power, Sex, Suicide by Nick Lane (2006) section "Gene loss as an evolutionary trajectory" puts it well:
One of the most extreme examples of gene loss is Rickettsia prowazekii, the cause of typhus. [...] Over evolutionary time Rickettsia has lost most of its genes, and now has a mere  protein-coding genes left. [...] Rickettsia is a tiny bacterium, almost as small as a virus, which lives as a parasite inside other cells. It is so well adapted to this lifestyle that it can no longer survive outside its host cells. [...] It was able to lose most of its genes in this way simply because they were not needed: life inside other cells, if you can survive there at all, is a spoonfed existence.
and also section "How to lose the cell wall without dying" page 184 has some related mentions:
While many types of bacteria do lose their cell wall during parts of their life cycle only two groups of prokaryotes have succeeded in losing their cell walls permanently, yet lived to tell the tale. It's interesting to consider the extenuating circumstances that permitted them to do so.
[...]
One group, the Mycoplasma, comprises mostly parasites, many of which live inside other cells. Mycoplasma cells are tiny, with very small genomes. M. genitalium, discovered in 1981, has the smallest known genome of any bacterial cell, encoding fewer than 500 genes. M. genitalium, discovered in 1981, has the smallest known genome of any bacterial cell, encoding fewer than 500 genes. [...] Like Rickettsia, Mycoplasma have lost virtually all the genes required for making nucleotides, amino acids, and so forth.

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