X-ray crystallography by Ciro Santilli 37 Updated 2025-07-16
One of its main applications is to determine the 3D structure of proteins.
Sometimes you are not able to crystallize the proteins however, and the method cannot be used.
Crystallizing is not simple because:
  • you need a considerable amount of the protein
  • sometimes it only crystallizes if you add some extra small chemical that stabilizes it
Cryogenic electron microscopy can sometimes determine the structures of proteins that failed crystallization.
Dojo by Ciro Santilli 37 Updated 2025-07-16
"Dojo" is the japanese version of the word that unfortunately came to dominate in the West, the original is of course Chinese Dao4 chang3 (道場) which means:
  • dao4 (道): Taoism, the Enlightned Path to something
  • chang3 (場): suffix indicating "a place where you do something"
Ciro Santilli would like to fully understand the statements and motivations of each the problems!
Easy to understand the motivation:
Hard to understand the motivation!
Alexander Grothendieck by Ciro Santilli 37 Updated 2025-07-16
This dude looks like a God. Ciro Santilli does not understand his stuff, but just based on the names of his theories, e.g. "Yoga of anabelian algebraic geometry", and on his eccentric lifestyle, it is obvious that he was in fact a God.
Linear function by Ciro Santilli 37 Updated 2025-07-16
The term is not very clear, as it could either mean:
Riemann integral by Ciro Santilli 37 Updated 2025-07-16
The easy and less generic integral. The harder one is the Lebesgue integral.

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