KCNJ8 is a gene that encodes a protein known as the potassium ion channel, specifically the K(ATP) channel, which is sensitive to intracellular ATP levels. This channel plays a crucial role in regulating cellular excitability, particularly in muscle and neuronal tissues. KCNJ8 is part of the inwardly rectifying potassium channel family and is typically associated with controlling various physiological processes, including insulin secretion in pancreatic beta cells, vascular smooth muscle contraction, and cardiac action potentials.
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