Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful analytical technique used primarily to determine the structure and dynamics of molecules in various fields, including chemistry, biochemistry, and medicine. The technique leverages the magnetic properties of certain atomic nuclei. Here’s how it works: ### Basic Principles: 1. **Nuclear Spin**: Some nuclei have a property called "spin," which gives them a magnetic moment.
A benchtop nuclear magnetic resonance (NMR) spectrometer is a compact and user-friendly instrument used for molecular structure determination and analysis based on the principles of nuclear magnetic resonance. Unlike traditional large-scale NMR spectrometers, which are typically housed in dedicated laboratories and require significant infrastructure, benchtop NMR spectrometers are smaller, more affordable, and easier to operate.
Chemical shift is a term used in nuclear magnetic resonance (NMR) spectroscopy to describe the variation in resonance frequency of nuclei in a magnetic field due to their electronic environment. When atomic nuclei are placed in a magnetic field, they resonate at specific frequencies. However, the presence of surrounding electrons influences these frequencies, leading to shifts in the resonance peaks observed in an NMR spectrum. ### Key Points about Chemical Shift: 1. **Units**: Chemical shift is measured in parts per million (ppm).
The Ernst angle is a concept from the field of nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI). It refers to a specific angle of rotation that maximizes the signal intensity in certain imaging or relaxation sequences. In longitudinal relaxation, the Ernst angle is associated with the optimal flip angle that maximizes the signal-to-noise ratio (SNR) for a given repetition time (TR) in an NMR experiment.
In vivo magnetic resonance spectroscopy (MRS) is a non-invasive imaging technique used to study the biochemical composition of tissues in living organisms, typically in humans. It operates on principles similar to those of magnetic resonance imaging (MRI), utilizing strong magnetic fields and radiofrequency pulses to detect and analyze the magnetic properties of atomic nuclei in various molecules.
Knight shift refers to a phenomenon observed in nuclear magnetic resonance (NMR), particularly in the context of studying the electronic properties of materials. Named after physicist William D. Knight, the Knight shift is a measure of the change in the resonance frequency of nuclei in a magnetic field due to the influence of the local electronic environment.
The Nuclear Overhauser Effect (NOE) is a phenomenon observed in nuclear magnetic resonance (NMR) spectroscopy that arises from the interaction between spin states of neighboring nuclear spins, typically hydrogen nuclei (protons). It is a result of the cross-relaxation process between closely spaced nuclei, which can enhance the NMR signal of certain nuclei in the presence of others.
Nuclear acoustic resonance (NAR) is a phenomenon that combines principles of nuclear magnetic resonance (NMR) with acoustic waves. It primarily focuses on interactions between nuclear spins and acoustic vibrations in a material. This concept can be understood within the context of solid-state physics and materials science. In NAR, the spins of nuclei are influenced by acoustic waves, which can lead to transitions between quantum states of the nuclei.
Nuclear Magnetic Resonance (NMR) database methods refer to the use of NMR spectroscopy data in conjunction with databases to analyze, interpret, and predict molecular structures and properties. NMR spectroscopy is a powerful analytical technique used to determine the structure, dynamics, and environment of molecules.
A Nuclear Magnetic Resonance (NMR) spectra database is a collection of NMR spectra that have been produced from various chemical compounds. NMR spectroscopy is an analytical technique used to determine the structure, dynamics, and environment of molecules based on the magnetic properties of certain nuclei. The most commonly studied nucleus is hydrogen (\(^1H\)) but carbon (\(^13C\)), nitrogen (\(^15N\)), and phosphorus (\(^31P\)) are also frequently used.
Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful analytical technique used to determine the structure and dynamics of molecules, including carbohydrates. In the context of carbohydrates, NMR spectroscopy provides valuable information about their chemical structure, conformation, and interactions. ### Key Aspects of NMR Spectroscopy of Carbohydrates: 1. **Principle**: NMR relies on the magnetic properties of certain atomic nuclei, primarily hydrogen (^1H) and carbon (^13C) nuclei in carbohydrates.
Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful analytical technique used to study the structure and dynamics of molecules, particularly in organic chemistry and biochemistry. When applied to nucleic acids, such as DNA and RNA, NMR spectroscopy provides insights into their structure, conformation, interactions, and dynamics at the atomic level.
Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical technique used to determine the structure, dynamics, and interactions of proteins and other biomolecules at the atomic level. The method relies on the magnetic properties of certain atomic nuclei, primarily hydrogen (¹H), carbon (¹³C), nitrogen (¹⁵N), and phosphorus (³¹P). Here’s a more detailed overview of how NMR spectroscopy works in the context of proteins: ### Basic Principles of NMR 1.
Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful analytical technique used to determine the structure of molecules, including stereoisomers. It relies on the magnetic properties of atomic nuclei, particularly those of hydrogen (^1H) and carbon (^13C), to gather information about the molecular environment of these nuclei. ### Key Concepts of NMR Spectroscopy: 1. **Nuclei and Magnetic Fields**: NMR exploits the magnetic properties of certain nuclei.
Paramagnetic nuclear magnetic resonance (NMR) spectroscopy is a specialized technique that takes advantage of the magnetic properties of certain paramagnetic species—atoms or molecules that have unpaired electrons, which can contribute to a magnetic moment. This technique is particularly useful for studying the structure and dynamics of molecules that contain transition metal ions or free radicals, which are commonly paramagnetic.
Proton nuclear magnetic resonance (¹H NMR) is a powerful analytical technique used in chemistry and biochemistry to determine the structure of organic compounds and the dynamics of molecular systems. It relies on the magnetic properties of certain atomic nuclei, in this case, the hydrogen nucleus (proton). In ¹H NMR, a sample is placed in a strong magnetic field and subjected to radiofrequency radiation. The protons within the sample resonate at specific frequencies that depend on their chemical environment.
Residual chemical shift anisotropy (RCSA) refers to a phenomenon observed primarily in the context of nuclear magnetic resonance (NMR) spectroscopy, particularly in solid-state NMR and biomolecular NMR. It is an important concept in understanding how molecular dynamics and interactions affect chemical shifts of nuclei in a sample. In NMR, chemical shifts arise from the magnetic environments surrounding nuclei, which can be influenced by the electronic environment created by nearby atoms and molecular structure.
The Solomon equations refer to a set of equations used primarily in the context of hydrology and environmental science to describe the movement of water through unsaturated soils. Named after the work of Professor L. L. Solomon, these equations are used to model the flow of moisture in relation to variables such as soil saturation, porosity, and hydraulic conductivity.
Triple-resonance nuclear magnetic resonance (NMR) spectroscopy is a sophisticated technique used primarily in the study of proteins and other complex molecules. This method exploits the interactions between three different nuclear spins (typically involving different isotopes of atoms such as hydrogen, carbon, and nitrogen) to provide detailed information about molecular structure, dynamics, and interactions.
Two-dimensional nuclear magnetic resonance (2D NMR) spectroscopy is a sophisticated technique used to analyze the structural and dynamic properties of molecules, particularly in organic chemistry and biochemistry. This method extends traditional one-dimensional NMR spectroscopy by providing additional information about the interactions between nuclear spins in a molecule. ### Key Features of 2D NMR Spectroscopy: 1. **Dimension Expansion**: In 2D NMR, the information is spread across two frequency dimensions rather than one.
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Nuclear magnetic resonance spectroscopy by 
Ciro Santilli 37 Updated 2025-06-17 +Created 1970-01-01
Ciro Santilli 37 Updated 2025-06-17 +Created 1970-01-01Used to identify organic compounds.
Seems to be based on the effects that electrons around the nuclei (shielding electrons) have on the outcome of NMR.
So it is a bit unlike MRI where you are interested in the position of certain nuclei in space (of course, these being atoms, you can't see their positions in space).
What's Nuclear Magnetic Resonance by Bruker Corporation (2020)
Source. Good 3D animations showing the structure of the NMR machine. We understand that it is very bulky largely due to the cryogenic system. It then talks a bit about organic compound identification by talking about ethanol, i.e. this is NMR spectroscopy, but it is a bit too much to follow closely. Basically the electron configuration alters the nuclear response somehow, and allows identifying functional groups.