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Intrinsic dynamics of an enzyme underlies catalysis by Elan Z. Eisenmesser and others by
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Nature 438, 117–121 (2005). Publisher record. Primary article or institutional bibliographic record.
A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis by Gira Bhabha and others by
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Science 332, 234–238 (2011). Publisher record. Primary article or institutional bibliographic record.
Randomization of genes by PCR mutagenesis by R. Craig Cadwell and Gerald F. Joyce by
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PCR Methods and Applications 2, 28–33 (1992). Publisher record. Primary article or institutional bibliographic record.
Trinucleotide phosphoramidites: ideal reagents for the synthesis of mixed oligonucleotides for random mutagenesis by Bernhard Virnekas and others by
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Nucleic Acids Research 22, 5600–5607 (1994). Publisher record. Primary article or institutional bibliographic record.
DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution by Willem P. C. Stemmer by
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PNAS 91, 10747–10751 (1994). Publisher record. Primary article or institutional bibliographic record.
Structure and function of the feed-forward loop network motif by Shmoolik Mangan and Uri Alon by
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Speciation driven by natural selection in Drosophila by Mohamed A. Noor by
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By Mohamed A. Noor. Nature 375, pp. 674–675; geographic variation in female discrimination against D. persimilis.
The Genetics of Speciation by Reinforcement by Daniel Ortiz-Barrientos and others by
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By Daniel Ortiz-Barrientos. PLoS Biology 2, e416; crosses, mate discrimination and the genetic basis of enhanced isolation.
Experimentally induced innovations lead to persistent culture via conformity in wild birds by Lucy M. Aplin and others by
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By Lucy M. Aplin. Nature 518, pp. 538–541; seeded puzzle-box techniques and social diffusion in wild great tits.
Natural Behavior Polymorphism Due to a cGMP-Dependent Protein Kinase of Drosophila by K. A. Osborne and others by
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By K. A. Osborne. Science 277, pp. 834–836, Tables 1–3; foraging variants, kinase activity and transgenic rescue.
Three-butterfly system provides a field test of müllerian mimicry by Durrell D. Kapan by
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By Durrell D. Kapan. Nature 409, pp. 338–340; H. cydno release experiments, local co-models and release density.
optix Drives the Repeated Convergent Evolution of Butterfly Wing Pattern Mimicry by Robert D. Reed and others by
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By Robert D. Reed. Science 333, pp. 1137–1141; mapping, expression and population genetics of red wing patterning.
Butterfly genome reveals promiscuous exchange of mimicry adaptations among species by The Heliconius Genome Consortium by
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By The Heliconius Genome Consortium. Nature 487, pp. 94–98; genomic comparisons and introgression around mimicry loci.
Resistance to American foulbrood disease by honey bee colonies Apis mellifera bred for hygienic behavior by Marla Spivak and Gary S. Reuter by
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By Marla Spivak. Coauthor: Gary S. Reuter. Apidologie 32, pp. 555–565; selected hygienic colonies, brood assays and pathogen challenge.
Evidence for trans-generational medication in nature by Thierry Lefèvre and others by
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By Thierry Lefèvre. Ecology Letters 13, pp. 1485–1493; infected monarch mothers, oviposition choice and offspring parasite growth.
Differential Effects of Lipopolysaccharide on Pup Retrieving and Nest Building in Lactating Mice by Arnaud Aubert and others by
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By Arnaud Aubert. Brain, Behavior, and immunity 11, pp. 107–118; immune challenge, maternal behaviour and ambient temperature.
Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour by Anthony J. Filiano and others by
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By Anthony J. Filiano. Nature 535, pp. 425–429, Figs. 1–2; immune deficiency, IFN-γ interventions, neural physiology and social preference.
Chimpanzees: Self-Recognition by Gordon G. Gallup Jr. by
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By Gordon G. Gallup Jr.. Science 167, pp. 86–87; mirror exposure, hidden dye marks and self-directed touching.
Mirror self-recognition in the bottlenose dolphin: A case of cognitive convergence by Diana Reiss and Lori Marino by
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By Diana Reiss. Coauthor: Lori Marino. PNAS 98, pp. 5937–5942; marked and sham-marked dolphins and mirror-oriented body inspection.
Self-recognition in an Asian elephant by Joshua M. Plotnik and others by
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By Joshua M. Plotnik. PNAS 103, pp. 17053–17057; large accessible mirror, visible and sham marks, one of three subjects passing.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.Figure 3. Visual Studio Code extension installation.Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





