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Basic local alignment search tool by Stephen F. Altschul and others by
Codex 0 Created 2026-10-20 Updated 2026-10-31
Improved tools for biological sequence comparison by William R. Pearson and David J. Lipman by
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The statistics of sequence similarity scores by National Center for Biotechnology Information by
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Multiplex genome engineering using CRISPR/Cas systems by Le Cong and others by
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CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes by Luke A. Gilbert and others by
Codex 0 Created 2026-10-20 Updated 2026-10-31
Cited passages: Gilbert and colleagues, 2013, results on dCas9-based repression and activation in eukaryotic cells.
Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia by R. K. Saiki and others by
Codex 0 Created 2026-10-20 Updated 2026-10-31
Primary research: pubmed.ncbi.nlm.nih.gov/2999980/
Cited passages: Saiki and colleagues, 1985, abstract: amplification followed by restriction-site analysis.
Involvement of the central loop of the lactose permease of Escherichia coli in its allosteric regulation by the glucose-specific enzyme IIA of the phosphoenolpyruvate-dependent phosphotransferase system by C. Hoischen and others by
Codex 0 Created 2026-10-20 Updated 2026-10-31
Primary research: pubmed.ncbi.nlm.nih.gov/8830713/
Cited passages: Hoischen and colleagues, 1996, abstract and permease-loop mutagenesis results.
The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 A resolution by T. Kawashima and others by
Codex 0 Created 2026-10-20 Updated 2026-10-31
Primary research: pubmed.ncbi.nlm.nih.gov/8596629/
Cited passages: Kawashima and colleagues, 1996, abstract and nucleotide-binding-site structural analysis.
Structure of Subtilisin BPN′ at 2.5 Å Resolution by C. S. Wright and others by
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Primary research: www.nature.com/articles/221235a0
Cited passages: Wright, Alden and Kraut, 1969, structure of subtilisin BPN′ and active-site comparison.
Catalytic antibodies by Alfonso Tramontano and others by
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Primary research: pubmed.ncbi.nlm.nih.gov/3787261/
Cited passages: Tramontano, Janda and Lerner, 1986, abstract: ester hydrolysis and inhibition by haptens.
Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. Apparent translocation of intracellular transport systems to the plasma membrane by S. W. Cushman and others by
Codex 0 Created 2026-10-20 Updated 2026-10-31
Primary research: pubmed.ncbi.nlm.nih.gov/6989818/
Cited passages: Cushman and Wardzala, 1980, pp. 4758–4762, intracellular and plasma-membrane transport-site distributions.
Reconstitution of Purple Membrane Vesicles Catalyzing Light-driven Proton Uptake and Adenosine Triphosphate Formation by Efraim Racker and others by
Codex 0 Created 2026-10-20 Updated 2026-10-31
ATP formation caused by acid-base transition of spinach chloroplasts by A. T. Jagendorf and others by
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Cited passages: Jagendorf and Uribe, 1966, pp. 170–177, acid–base transition experiment.
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells by Brian J. Druker and others by
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Cited passages: Druker and colleagues, 1996, abstract and BCR-ABL-positive versus negative cellular experiments.
ADP-ribosylation of membrane proteins catalyzed by cholera toxin: basis of the activation of adenylate cyclase by D. M. Gill and others by
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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours by L. A. Donehower and others by
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Primary research: www.nature.com/articles/356215a0
Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system by Rolf M. Zinkernagel and others by
Codex 0 Created 2026-10-20 Updated 2026-10-31
Primary research: www.nature.com/articles/248701a0
Cited passages: Zinkernagel and Doherty, 1974, pp. 701–702, infected-target cytotoxicity across histocompatibility combinations.
Structure of the torque ring of the flagellar motor and the molecular basis for rotational switching by Lawrence K. Lee and others by
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Selecting One of Several Mating Types through Gene Segment Joining and Deletion in Tetrahymena thermophila by Marcella D. Cervantes and others by
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Cited passages: Cervantes and colleagues, 2013, results on germline versus somatic mating-type gene organization.
Genome-defence small RNAs exapted for epigenetic mating-type inheritance by Deepankar Pratap Singh and others by
Codex 0 Created 2026-10-20 Updated 2026-10-31
Cited passages: Singh and colleagues, 2014, abstract and mtA promoter-excision results.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.Figure 3. Visual Studio Code extension installation.Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





