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Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons by Orly L. Wapinski and others by
Codex 0 Created 2026-10-20 Updated 2026-10-31
Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding by David J. Haile and others by
Codex 0 Created 2026-10-20 Updated 2026-10-31
PNAS 89, 11735–11739 (1992). Publisher record. Primary article or institutional record.
An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis by Ameen A. Salahudeen and others by
Codex 0 Created 2026-10-20 Updated 2026-10-31
Identification of the iron-responsive element for the translational regulation of human ferritin mRNA by Matthias W. Hentze and others by
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Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation by John L. Casey and others by
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Coordinated remodeling of cellular metabolism during iron deficiency through targeted mRNA degradation by Sergi Puig and others by
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Identification of a novel iron-responsive element in murine and human erythroid delta-aminolevulinic acid synthase mRNA by Thomas Dandekar and others by
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The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA by Juan Valcárcel and others by
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Splicing regulation at the second catalytic step by Sex-lethal involves 3′ splice site recognition by SPF45 by María José Lallena and others by
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Structure of PTB bound to RNA: specific binding and implications for splicing regulation by Florian C. Oberstrass and others by
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RNA looping by PTB: evidence using FRET and NMR spectroscopy for a role in splicing repression by Rajan Lamichhane and others by
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PNAS 107, 4105–4110 (2010). Publisher record. Primary article or institutional record.
Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB by Miriam Llorian and others by
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Nature Structural & Molecular Biology 17, 1114–1123 (2010). Publisher record. Primary article or institutional record.
Single-Molecule Imaging Reveals Translation of mRNAs Localized to Stress Granules by Daniel Mateju and others by
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biological cell 183, 1801–1812.e13 (2020). Publisher record. Primary article or institutional record.
G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits by Nancy Kedersha and others by
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Journal of biological cell Biology 212, 845–860 (2016). Publisher record. Primary article or institutional record.
Crystal structure of the nucleosome core particle at 2.8 Å resolution by Karolin Luger and others by
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Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position by Jason D. Buenrostro and others by
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ChromEMT: Visualizing 3D chromatin structure and compaction in interphase and mitotic cells by Horng D. Ou and others by
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A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping by Suhas S. P. Rao and others by
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Cohesin loss eliminates all loop domains by Suhas S. P. Rao and others by
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Identification of in vivo DNA targets of chromatin proteins using tethered Dam methyltransferase by Bas van Steensel and Steven Henikoff by
Codex 0 Created 2026-10-20 Updated 2026-10-31
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.Figure 3. Visual Studio Code extension installation.Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





