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by Ciro Santilli (@cirosantilli, 37)

Operon vs transcription unit

 ... Level of organization of bodies Molecular biology DNA RNA Transcription (biology) Operon
 0 By others on same topic  0 Discussions  Updated 2025-05-13  +Created 1970-01-01  See my version
Consider the E. Coli K-12 MG1655 operon thrLABC.
That single operon can produce two different mRNA transcription units:
  • thrL only, the transcription unit is also called thrL: biocyc.org/ECOLI/NEW-IMAGE?object=TU0-42486
  • thrL + thrA + thrB + thrC all together, the transcription unit is called thrLABC: biocyc.org/ECOLI/NEW-IMAGE?type=OPERON&object=TU00178
The reason for this appears to be that there is a rho-independent termination region after thrL. But then under certain conditions, that must get innactivated, and then the thrLABC is produced instead.

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