A serotonin receptor subtype implicated in particular local circuits, including some threat-related extended-amygdala pathways.
It is a G protein-coupled receptor commonly linked to Gq-family signalling. Its contribution to behaviour depends on which cells express it and which local circuit receives the signal; receptor identity alone does not predict one universal behavioural effect. [ref]
Molecular Biology of the Cell, 4th edition by Bruce Alberts and others. Chapters 3, 6 and 15, protein function, translation and cell signalling
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