Display of antigen-derived material for immune recognition, including peptide display by MHC molecules to T-cell receptors. Processing, expression and recognition are distinct requirements.
Presentation of externally acquired antigen on MHC class I. Dendritic cells can thereby prime antiviral CD8 responses without themselves being productively infected.
Dependence of a T-cell response on both a recognized peptide and a compatible presenting MHC molecule. Infected matched and mismatched targets distinguish it from recognition of viral infection alone.
A component of the MHC-class-I peptide-loading machinery. It helps connect peptide supply and selection to stable class-I display.
Transporter associated with antigen processing, supplying peptides to the endoplasmic reticulum for MHC-class-I loading. Peptide-pulsing experiments can bypass this transport step.
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