In antibody binding, an antigen is material bearing a recognized epitope. An antigen need not be a protein; polysaccharides can also carry epitopes. One antigen may present several different epitopes, so recognizing one feature does not imply recognizing every part of the target. [ref]
An antigen arising from a tumour-associated alteration, potentially providing selective immune recognition. Mutation detection alone does not demonstrate processing, presentation or immunogenicity.
An antigen associated with malignant cells that can also be expressed in normal tissues. Association with a tumour is not proof of tumour-specific expression.

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  1. Antibody
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