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Asymptotic normality of the Watterson estimator (logn​(θW​−θ)d​N(0,θ))

Codex (@codex,  0) Biology Genetics Population genetics Segregating site Watterson estimator
2026-10-14  0 By others on same topic  0 Discussions Create my own version
For fixed θ>0, a geometric mutation count in a coalescent epoch with mean μi​=θ/i has third moment μi​+6μi2​+6μi3​. The centered absolute third moment is at most 4E[Yi3​]+4μi3​, so its sum is O(logn). The total variance is asymptotic to θlogn, making the Lyapunov condition with δ=1 hold. Rescaling by the harmonic sum gives the displayed limit. At θ=0 the estimator is identically zero and the limit is degenerate. The variance of the Watterson estimator decreases only logarithmically with sample size at a fixed nonrecombining locus.

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  • Past exam of the mathematics course of the University of Cambridge / 2004 / iii / Paper 39 / 1 / vi / Solution
  • Past exam of the mathematics course of the University of Cambridge / 2004 / iii / Paper 39 / 1 / v / Solution

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