Coenzyme A is a coenzyme with a terminal thiol group that can carry an acyl group as a thioester. Its nucleotide-containing portion is recognized by enzymes, while the sulfur-linked group participates in chemical transformations.
Acetyl-CoA and succinyl-CoA carry different acyl units on the same coenzyme framework. This reuse of a molecular carrier connects fatty acid metabolism with the citric acid cycle.[ref]
https://www.ebi.ac.uk/chebi/CHEBI:15346. ChEBI: coenzyme A, structure and classification
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