For a head sampling phases uniformly during steady sliding, its mean force is times the phase-average bound probability. In the limit of spatially gated myosin attachment, integrating the three intervals gives
The first integral is bounded by , and the last by . Relative to the plateau contribution, they are negligible when and , respectively. Therefore
This is a constant-force spatially gated motor approximation: complete detachment between binding windows, a narrow attachment window, a short detachment tail and essentially fixed sliding velocity. In particular, need not be small.
Put and . The constant-force spatially gated motor produces
The limit is approached after the periodic steady state is established; at exactly arbitrary initially bound heads in inactive phase intervals need not equilibrate. The curve decreases from and has formal large- tail . Extrapolation of that tail beyond the small- detachment assumptions is not controlled.
Sign inconsistency in the printed force balance. For a positive viscous drag coefficient , the signed drag force is . The printed cannot give the requested positive no-load contraction speed: both last terms are positive when . With , the left side starts at and may have zero, one or two positive roots depending on parameters; the requested usual load construction is not implied by that equation.
The physical linear-drag load curve for a spatially gated motor uses
On the same axes plot the positive drag magnitude and the decreasing motor force . The no-load speed is their intersection. For opposing load , intersect with the parallel raised line ; equivalently intersect with . Drop verticals to the speed axis. The loaded speed obeys . Each intersection is unique because decreases and increases. The signed drag is also indicated below the axis in the sketch.
Figure 1.
Motor-force and drag construction after correcting the printed drag sign
. Details.