First refine the ephemeris, planetary mass, stellar radius, and stellar variability using exoplanet transit photometry and the radial-velocity method. Then combine observations that probe different regions rather than relying on one spectrum. A present-day programme could use the following complementary measurements; in the 2019 setting of the paper, James Webb Space Telescope observations would have been a future capability.
Together these address aerosols, molecular composition, elemental enrichment, vertical thermal structure, horizontal heat transport, winds, and escape. Repeat key events and monitor stellar activity, since stellar contamination and instrumental trends can imitate atmospheric signals. Use actual brightness, saturation limits, and predicted feature amplitudes to choose observing modes and exposure times.