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For fixed $(P,Q)\ne (0,0)$ the effective Fermi interaction predicts $d\sigma /d\Omega \propto G_F^{2}s$. The angular odd term integrates to zero, while $\int d\Omega (1+{\cos }^2\theta )=16\pi /3$, soThe corresponding fixed-spin scattering amplitudes grow as $G_{F}s$, eventually conflicting with partial-wave unitarity. This is a failure of extrapolating the effective field theory, whose contact approximation requires $s\ll M_W^2$, not a failure of the Standard Model.

Restoring the virtual W boson Feynman propagator replaces its constant low-energy denominator by $M_W^2/(M_W^2-s)$, away from the resonance. The massless external Dirac equations give zero contraction of each current with the exchanged momentum, so the longitudinal numerator does not contribute. Its squared modulus multiplies the effective cross-section. For $s\gg M_W^2$ the resulting tree-level rate decreases as $1/s$ rather than growing as $s$. Near the pole one must include the W boson decay width. These statements assume the same massless conserved external currents; the contact expression alone is not valid there.

Let $|1⟩=|D^0⟩$, $|2⟩=|{\bar{D}}^0⟩$. In the rest frame, the CPT theorem interchanges these states up to irrelevant phases. For the weak Hamiltonian operator $H^{\prime }$, with $H^{\prime }=H^{\prime †}$, and its antiunitary CPT symmetry operator $\Theta$,Its diagonal matrix elements are real by Hermitian conjugation, soIn the specified phase convention, the CP symmetry operator on this two-state subspace is $-{\sigma }_x$. If the weak interaction preserves CP symmetry, ${\sigma }_{x}R{\sigma }_x=R$, givingIndependently, Hermitian conjugation gives $R_{21}=R_{12}^{\ast }$ for this $H^{\prime }$. Hence CP symmetry makes the off-diagonal element real in this convention; that conjugation relation alone does not imply CP symmetry.

For neutral meson mixing described by the decay-effective Hamiltonian operator $R=M-i\Gamma /2$, the effective matrix is generally not a Hermitian matrix. The CPT constraints on neutral-meson mixing still give equality of the complex diagonal entries, expressing equal masses and total decay widths, and CP symmetry gives equality of the off-diagonal entries in the specified convention. One must not additionally impose $R_{21}=R_{12}^{\ast }$ on this decay-effective matrix.

The tree-level Feynman diagrams contain an unchanged spectator quark, of up quark flavour and the two possible weak charged current transitions of the charm antiquark:

For ${\bar{D}}^0\to K^{+}{\pi }^{-}$, $\bar{c}\to \bar{s}{W}^{-}$ and $W^{-}\to d\bar{u}$. The spectator quark combines with $\bar{s}$ into the kaon $K^{+}=u\bar{s}$, while $d\bar{u}$ forms the pion ${\pi }^{-}$. The Cabibbo-Kobayashi-Maskawa matrix factor is $V_{cs}{V}_{ud}^{\ast }$.

For ${\bar{D}}^0\to K^{-}{\pi }^{+}$, $\bar{c}\to \bar{d}{W}^{-}$ and $W^{-}\to s\bar{u}$. The spectator quark combines with $\bar{d}$ into the pion ${\pi }^{+}=u\bar{d}$, while $s\bar{u}$ forms the kaon $K^{-}$. The Cabibbo-Kobayashi-Maskawa matrix factor is $V_{cd}{V}_{us}^{\ast }$.

Neglecting neutral D-meson mixing and assuming comparable strong interaction matrix elements, the relative direct decay widths areHere ${\theta }_C$ is the Cabibbo angle. The second process is doubly Cabibbo suppressed: it contains two small Cabibbo suppression factors in its amplitude. The Cabibbo angle estimate assumes similar Quantum chromodynamics matrix elements; it is not an exact rate equality.