I would not assign the lunar mare an automatic terrestrial 100–125 km compensation level. For present-day mare basins, a local equal-column-mass model may have no physically valid compensation depth; first test whether lithospheric flexure supports the load. For ancient thermally driven subsidence that did relax, choose a common datum beneath the cooling layer in deformable lunar mantle appropriate to that epoch.
The Moon is smaller than Earth and has lost a larger fraction of its original heat. Its cold, mechanically strong outer shell can be much thicker relative to its radius than the terrestrial oceanic lithosphere. Lunar mare basalts filled pre-existing impact basins: their loading, basin excavation, mantle uplift, cooling and the evolving strength of the lithosphere all matter. A thick elastic lithosphere can support lateral stress differences, so equal column mass need not hold even after a long time. The strong gravity anomalies of lunar mascons, measured by GRAIL, are evidence that the present mare-basin system is not everywhere locally compensated.[ref]
For an explicitly assumed ancient relaxed thermal model, estimate its thermal penetration depth from thermal diffusivity and the elapsed cooling time, infer the contemporaneous mechanical lid from gravity-topography admittance or basin deformation, and place below that layer where lateral pressure anomalies relax. For example, a hypothetical several-hundred-kilometre-thick lid requires a deeper datum than that lid, not the shallow crust-mantle boundary. The paper supplies neither an epoch-specific thermal model nor a load wavelength, so a unique kilometre value is not determined. If the chosen datum is a substantial fraction of the lunar radius, spherical geometry and radial variation in gravity must replace the flat, constant-gravity column approximation.
Does the Moon have an asthenosphere? Not a demonstrated shallow, globally connected Earth-like layer underlying mobile plates; but “no weak or partially molten mantle anywhere, ever” is too strong. Apollo lunar seismology indicates a cold outer interior and more attenuating deep regions. Reanalyses support a deep low-velocity or partially molten region near the lunar core, while lunar laser ranging and tidal Love numbers constrain deep deformability and tidal dissipation. Such a deep weak region is sometimes called a lunar asthenosphere; it is not automatically the correct local compensation surface for a mare load.[ref]
The inferred melt fraction and distribution remain model dependent: Dissipation at tidal and seismic frequencies in a melt-free Moon by Francis Nimmo and others demonstrates that much of the dissipation can also be explained by hot solid-state anelasticity, although its model does not reproduce every frequency-dependent constraint. The Moon was hotter during mare emplacement and could relax loads differently then. Choose the datum from the relevant thermal and mechanical history, or use a flexural model when local isostasy fails.