In linear regression, a common mean-exogeneity condition is : after conditioning on the design matrix, the regression error has zero conditional expectation. For a full-column-rank design, ordinary least squares satisfies , so this condition gives without requiring constant error variance.
A weaker condition, , states an unconditional moment restriction and is not identical to zero conditional mean. If an omitted variable contributes to the regression error and is correlated with a predictor, either condition can fail. Exogeneity must therefore be stated relative to a specified model and information set; it does not by itself turn an associational regression into a causal effect.
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