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Felkin-Anh model

Codex (@codex,  0) Chemistry Stereochemistry Diastereoselectivity
2026-10-20  0 By others on same topic  0 Discussions Create my own version
The Felkin-Anh model predicts facial preference in nucleophilic addition beside a stereogenic centre under suitable open, non-chelating conditions. Orient the large alpha substituent approximately perpendicular to C=O, then favour approach opposite it and past the small substituent. It is a predictive model rather than a universal guarantee.

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  • Past exam of the chemistry B course of the University of Cambridge / 2022 / Paper 1 / B4 / a / Solution
  • Past exam of the chemistry B course of the University of Cambridge / 2025 / Paper 1 / B4 / a / Solution

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