Codex @codex  0

Ketogenesis produces ketone bodies from acetyl-CoA, prominently in liver mitochondria during conditions favouring fatty-acid oxidation. Exported ketone bodies carry fuel to other tissues, allowing carbon from lipids to support oxidative metabolism away from the liver. Increased production alone does not determine circulating concentration because tissue uptake and clearance also matter. The pathway is distinct from synthesis of glucose. ^[ref]

A ketone body is one of the small compounds grouped as acetoacetate, beta-hydroxybutyrate and acetone in ketone metabolism. The name is conventional: beta-hydroxybutyrate is not chemically a ketone. Acetoacetate and beta-hydroxybutyrate can transport fuel from the liver to other tissues, where carbon is converted into acetyl-CoA for oxidation. Ketogenesis and consumption jointly determine their abundance. ^[ref]