Under Neyman allocation, sample sizes are proportional to the arm standard deviations. Here
For total size , the minimized asymptotic variance is
Equal allocation gives
The Neyman allocation therefore reduces the large-sample variance by , about of the equal-allocation variance.
Neyman allocation optimizes information and may allocate more patients to the arm whose Bernoulli variance is nearer its maximum at . The ethical allocation instead favors the arm with higher response probability. They coincide only for special parameter values; in general ethical gain is purchased with some loss of precision relative to Neyman allocation.
Writing and , Neyman allocation minimizes the variance at fixed total sample size and gives