Nicoleta Constantin helped reconstitute human DNA mismatch repair from purified components. A strand break on either side of a mismatch could direct correction, showing how strand information and repair proteins cooperate in selecting the sequence to replace.[ref]
Human mismatch repair: reconstitution of a nick-directed bidirectional reaction by Nicoleta Constantin and others. 2005, abstract: seven purified human activities and 3-prime/5-prime nick-directed repair
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