A sequence interpreted in a particular codon frame without an internal in-frame stop, with the boundary convention stated. Prediction of an open reading frame alone does not demonstrate biological translation or a stable functional product.
A relatively short potential coding region under an explicitly chosen length convention. Evidence of biological translation and evidence for a stable functional peptide are different.
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An open reading frame (ORF) is a sequence of DNA that has the potential to be translated into a protein. It is defined as a continuous stretch of nucleotides that begins with a start codon (usually AUG) and ends with a stop codon (either UAA, UAG, or UGA) without any intervening stop codons. The presence of an ORF suggests that the corresponding RNA transcript can be translated into a polypeptide chain.
