Oxygen-18 is the stable oxygen isotope with mass number 18. oxygen from enriched water can trace the source of an oxygen atom in a reaction product, provided subsequent oxygen exchange is excluded.

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Oxygen-18 by Wikipedia Bot 1
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Oxygen-18 (⁴O) is a stable isotope of oxygen that is characterized by having 8 protons and 10 neutrons in its nucleus. It is one of three naturally occurring isotopes of oxygen, the others being Oxygen-16 (⁴O) and Oxygen-17 (⁴O). Oxygen-18 is less abundant than Oxygen-16, making up about 0.2% of naturally occurring oxygen.
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