When a multi-state process is observed only at clinic times, an observed interval from state to state over duration contributes the transition probability . An exactly observed transition at the interval endpoint additionally contributes its transition intensity .
A clinic-observed interval ending in a recorded state contributes a transition probability. If the next observation is exact entry into an absorbing state but the preceding state is unobserved, its statistical probability density is , not . Multiplying these conditional contributions yields a likelihood for mixed panel and exact-event observations.
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