Past exam of the mathematics course of the University of Cambridge / 2004 / iii / Paper 38 / 1 / Solution

A censoring observation means an event time is not observed exactly: the information supplies a bound or interval instead. Under right censoring, one observes $X=\min (T,C)$ and the event indicator $\delta =1_{\{T\le C\}}$; if $\delta =0$, one knows only $T>C$. Left censoring gives an upper bound, while interval censoring locates the event between two observations.

Uninformative censoring means that, conditional on the covariates used in the analysis, the censoring mechanism supplies no additional information about the event time. Independence $T\perp C$ within those covariate strata is a sufficient formulation: subjects remaining in the observed risk set have the same future hazard as the corresponding event-free population. A fixed study cutoff unrelated to prognosis is an example of administrative censoring.

Informative censoring occurs when that condition fails. For example, students at high risk of leaving may also become harder to contact before their departure is formally recorded; censoring at loss of contact selectively removes high-risk students. Ordinary Kaplan–Meier estimator and Nelson–Aalen estimator calculations then use an unrepresentative risk set. The distinction determines whether ordinary survival estimates can be interpreted as population survival. Merely knowing that an observation is censored does not establish independence.