There are distinct interpolation nodes but only free coefficients in a polynomial of polynomial degree at most . Thus polynomial interpolation is possible precisely when the data satisfy one compatibility equation. To identify it, form the Lagrange interpolation polynomial through all the data:
This is the unique interpolation polynomial of polynomial degree at most . Its leading coefficient, which is also the order- divided difference, is
Consequently the required condition is
Necessity follows because any qualifying must equal by uniqueness of polynomial interpolation; sufficiency follows because removes the only possible term of polynomial degree from .
When this condition holds, a slightly shorter expression uses only the first interpolation nodes:
This polynomial agrees with at distinct points, so the root bound for a polynomial gives and hence as required. Equivalently, the compatibility condition says that this expression, evaluated at the last interpolation node, gives .

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