Apart from its multinomial coefficient, the likelihood is . Maximizing its logarithm subject to gives equal to a common multiplier, which is . Hence .
Under independence the log likelihood separates as . The two normalization constraints give and , so the fitted probabilities are . Therefore twice the difference of the maximized log likelihoods is
The unrestricted model has free parameters and the independence model has , leaving degrees of freedom for the table. Under the null, the likelihood-ratio statistic is asymptotically chi-squared with four degrees of freedom. Since , reject independence at the 0.1% significance level. This is evidence of association in the sampled variables; it does not by itself identify a causal direction.
Let be the clump size and put . The probability that all its members die, conditional on , is . Summing the geometric series gives
Subtracting from one yields , for .
Assuming independent clumps and independent repeats, the combined likelihood is proportional to . For its unique maximizer is . The relation between and is one-to-one, with . For this gives
If , the estimate is the boundary value zero; if strictly positive rates are required, it is only a limiting supremum. If , the likelihood approaches its supremum as and there is no finite estimate. These boundary cases explain when the printed logarithmic expression is finite.

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