Minimizing the sum of squared residuals gives the normal equations for linear least squares, . Full column rank makes positive definite and invertible, so the unique minimizer is
Because and , one has and
For the alternative linear estimator the corresponding general formulas are
No normality assumption on the errors is needed for these claims.
Unbiasedness of an estimator means unbiasedness for every parameter value, not just one chosen . Thus for every . Evaluating this identity on a basis, or identifying the two linear maps, gives
Put , with . Then , and therefore ; its transpose also vanishes. Expanding gives
Hence
The difference from the least-squares covariance is positive semidefinite, since . In particular its th diagonal entry is , proving every stated variance inequality. For estimating , prefer least squares: among linear unbiased estimators it has minimum variance, and therefore minimum mean squared error in that class. A competitor can tie if the first row of is zero. This is the Gauss-Markov theorem; it does not assert optimality against all biased or nonlinear estimators.

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