Scientific underdetermination limits what evidence alone establishes, but its practical consequences depend on the strength of the equivalence being claimed. Rival theories fitting present data need not agree on future observations. Rival formulations agreeing on every observable in a specified domain present a more persistent limitation within that domain.
With finitely many data points , suppose an interpolation polynomial fits all measurements. Then
also fits them for every . This proves nonuniqueness for a deliberately broad model class. It does not prove that all these functions are equally plausible physical theories. Constraints from independently tested mechanisms, bounds on derivatives, symmetries and the measurement process can sharply restrict the class. A new observation at a different point can also distinguish the displayed alternatives.
The Duhem problem concerns an additional kind of latitude: a prediction tests a theory together with auxiliary hypotheses. A mismatch can be assigned to different components. This is a reason to vary apparatus, calibrate independently and use multiple kinds of evidence. It is not a demonstration that any preferred theory can be made equally well supported by arbitrary repairs.[ref]
Exact empirical equivalence requires more. If two accounts supply identical probability distributions for all observations allowed by a stated setup, observations of that kind cannot favour one through their likelihoods. Bayesian inference makes the limitation explicit: posterior odds equal prior odds when the likelihood ratio is one. Declaring a prior preference does not transform it into new experimental discrimination.
Theories can nevertheless differ in explanatory organization, computational usefulness or how they connect with a larger domain. Those are legitimate questions, provided their role is stated. If a proposed new intervention distinguishes them, the equivalence did not cover that enlarged domain. If the difference is instead only a change of redundant description, treating it as two competing physical worlds may create a spurious dispute; gauge symmetry provides an important case requiring care.
For scientific practice, the appropriate response is model comparison with explicit assumptions, searches for discriminating tests and honest limits on what has been established. For scientific realism, enduring empirical equivalence challenges any claim that the evidence uniquely fixes a full ontology. It does not make precise predictions or experimental decisions impossible. Underdetermination is consequently a constraint on inference whose seriousness must be demonstrated case by case, rather than a general proof that all scientific reasoning is arbitrary.

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