Let label the incoming and outgoing fermion, and the incoming and outgoing antifermion. The bottom row of the figure gives the two tree-level Feynman diagrams:
Thus the Mandelstam variables in the two denominators are
The two scattering amplitude terms have a relative fermionic sign of minus when written with spinor products and . The overall phase depends on the chosen ordering of the external states. No channel joins an incoming fermion to an outgoing antifermion through a species-preserving Yukawa interaction.

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