Reciprocal guide-directed cleavage produces new piRNA ends from complementary precursor or target RNAs. A 10-nucleotide overlap of opposite-strand 5′ ends supports this mechanism but does not prove amplification in every piRNA pathway.

Ancestors (7)

  1. Piwi-interacting RNA
  2. Small regulatory RNA
  3. Ribonucleic acid
  4. Nucleic acid
  5. Polymer
  6. Chemistry
  7. Home

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