For positive concentrations and positive parameters, this reaction–diffusion system has homogeneous equilibrium and reaction Jacobian matrix . Its trace is and determinant is , making the equilibrium reaction-stable exactly when . Stable complex eigenvalues permit damped oscillations, which must be distinguished from sustained periodic oscillations.
A mode with squared wavenumber in the quadratic activator-inhibitor model has negative trace when . Its determinant is . A positive minimum location and a negative minimum require and , equivalent to . At onset, the double determinant root is . In a bounded domain an admissible nonzero spatial mode must additionally lie in the open negative-determinant band.
For the diffusionless quadratic activator-inhibitor model, choose the Dulac function . Then and , giving divergence . For it is strictly negative throughout the simply connected positive quadrant. Green's theorem rules out a periodic orbit: its boundary flux would be zero because the rescaled vector field is tangent to the orbit, while its interior divergence integral would be negative.

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