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Ryōji Noyori

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Created 2026-10-20 Updated 2026-11-05  0 By others on same topic  0 Discussions Create my own version
Ryōji Noyori developed chiral catalysts for asymmetric hydrogenation, in which addition of hydrogen preferentially produces one enantiomer. This work was recognized by the 2001 Nobel Prize in Chemistry.[ref]
The catalyst creates competing reaction paths with different activation free energies. It can thus favour one molecular handedness while being regenerated, linking catalysis with stereoselectivity.
Figure 1.
Portrait of Ryōji Noyori
. 日本学士院ホームページ (Japan Academy). CC BY 4.0, via Wikimedia Commons.  Source.
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  • Effects of HMPA on the Structure and Reactivity of the Lithium Enolate of Cyclopentanone in THF: The Dimer is Responsible for Alkylation and Proton Exchange Reactions by Masaaki Suzuki and others

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