An SH2 domain is a protein domain that recognizes a phosphotyrosine residue together with surrounding sequence features. This selective binding recruits a protein to a modified receptor or docking protein; it does not itself imply catalysis.[ref]
Signaling through Enzyme-Linked Cell-Surface Receptors. “Phosphorylated Tyrosines Serve as Docking Sites For Proteins With SH2 Domains”, Figure 15-53
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