A lymphocyte using a T-cell receptor for antigen recognition. Distinct populations have cytotoxic, helper, regulatory and memory functions.
A coreceptor usually associated with recognition of peptide–MHC-class-II complexes. CD4 T-cell populations coordinate and regulate immune responses in addition to other context-dependent activities.
A T-cell costimulatory receptor. Its interaction with B7 ligands on activated antigen-presenting cells contributes to naive-cell priming.
A coreceptor associated with recognition of peptide–MHC-class-I complexes by cytotoxic T cells. It contributes to binding and signalling without replacing T-cell-receptor specificity.
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